ISO-NOP30-L
一氧化氮感應器-30 micron
- Response Time:
<3 sec
- Lowest Detection
Limit: 1 nM
- Sensitivity: 1.4
pA/nM
- Application:
Tissue Bath
L-Shaped sensor for tissue bath
studies
The ISO-NOP30-L is a unique
L-shaped nitric oxide sensor designed specifically for use
in tissue bath studies and similar applications (see WPI's
MYOBATH). The shape of the sensor has been
engineered to facilitate placement of the electrode within
the lumen of the tissue vessel under study.
The response of a 7μm NO
sensor (ISO-NOP007) to successive additions of NO (100nM).
Inset shows the linearity of the resulting calibration
plot.
Simultaneous measurement of
force (top trace) and changes of NO concentration (lower
trace) in (A) the rat superior mesenteric artery relaxed
with ACh and (B) a small human artery relaxed with ACh and
SNAP. In this artery oxyhaemoglobin (oxyHb) partly
reversed the increase in NO concentration with only a
small change in force. [U. Simonsen, et al., J. Physiol.,
1999, 516: 271-282.] |
